The closest brewery to Roseburg to make the Top 50 U.S. Craft Brewing Companies list is #36 Ninkasi. Based on 2014 beer sales volume, the largest Oregon brewery is Bend’s Deschutes, 8th on the list, followed by Newport’s Rogue Ales at 32nd. The largest U.S, craft brewery is Pottsville, PA’s D.G. Yuengling and Son, which also happens to be America’s oldest operating brewery.
Source: Brewers Association